ITPR2 (1152-1164) Goat Polyclonal Antibody

SKU AP22536PU-N

ITPR2 (1152-1164) goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IHC
• Recommended Dilution: ELISA: 1/128000.; Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivity: Canine, Human, Monkey, Mouse, Rat
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of human ITPR2
• Specificity: This antibody detects IP3 receptor 2 / ITPR2 (Internal).
• Buffer: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide; State: Aff - Purified; State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: inositol 1,4,5-trisphosphate receptor type 2
• Database Link:
  Q14571
• Background: ITPR2 / IP3 Receptor Type 2 belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling.
• Synonyms: Type 2 InsP3 receptor, IP3R2

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway, Gap junction, GnRH signaling pathway, Long-term depression, Long-term potentiation, Oocyte meiosis, Phosphatidylinositol signaling system, Vascular smooth muscle contraction