PTGR1 Rabbit Polyclonal Antibody
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | Western blot: 1/500 - 1/1000. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Specificity | This antibody detects endogenous levels of LTB4DH protein. (region surrounding Leu105) |
| Buffer | Phosphate buffered saline (PBS), pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide |
| Concentration | 1.0 mg/ml |
| Purification | Affinity chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 36 kDa |
| Gene Name | prostaglandin reductase 1 |
| Database Link | |
| Background | The NADP(H)-dependent enzyme leukotriene 12-hydroxy dehydrogenase (LTB4DH) catalyzes double bond reductions and oxo-reductions in lipoxins (15-oxo-lipoxin A 4 ), leukotrienes (leukotriene B 4 ) and E/F prostaglandins (15-oxo prostaglandins). The reactions mediated by LTB4DH constitute an important inactivation pathway for these key lipid mediators involved in inflammation. LTB4DH belongs to the medium-chain dehydrogenase/reductase enzyme family. |
| Synonyms | PTGR1, LTB4DH, PGR-1, PGR1 |
| Reference Data | |
| Protein Families | Druggable Genome |
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