CD57 / HNK1 Rabbit Polyclonal Antibody

SKU AP20642PU-N

CD57 / HNK1 rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 1/50-1/200.; Western Blot: 1/500-1/1000.
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 3-50 of Human CD57.
• Specificity: This antibody detects endogenous levels of CD57 protein.; (region surrounding Val35)
• Buffer: Phosphate buffered saline (PBS), pH~7.2, 50% Glycerol; State: Aff - Purified; State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE); Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: ~38 kDa.
• Background: Over 100 cell surface markers have been identified through the use of monoclonal antibodies. Many of these markers have proven useful in identifying a specific subpopulation of cells within a mixed colony. Accordingly, these molecules have been assigned a “cluster of differentiation” (CD) designation. T lymphocytes displaying the natural killer (NK) cell marker CD57 (also designated Leu7) on their cell surface are distinguishable from other T cell subsets by their granular lymphocyte morphology and their clonal expansion in patients with AIDS and in recipients of bone marrow transplantation. CD57+ cells have also been shown to localize to sites of certain tumors and large numbers of these cells are detected in the synovial fluid from patients suffering from rheumatoid arthritis.
• Synonyms: HNK-1, LEU7, NK-1, NK-Cell marker, NK1

Reference Data