CD57 / HNK1 Rabbit Polyclonal Antibody

CAT#: AP20642PU-N

CD57 / HNK1 rabbit polyclonal antibody, Aff - Purified


USD 465.00

3 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Applications IHC, WB
Recommended Dilution Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Western Blot: 1/500-1/1000.
Reactivities Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 3-50 of Human CD57.
Specificity This antibody detects endogenous levels of CD57 protein.
(region surrounding Val35)
Formulation Phosphate buffered saline (PBS), pH~7.2, 50% Glycerol
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Preservative: 0.02% Sodium Azide
Concentration 1.0 mg/ml
Purification Affinity Chromatography using epitope-specific immunogen.
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Predicted Protein Size ~38 kDa.
Background Over 100 cell surface markers have been identified through the use of monoclonal antibodies. Many of these markers have proven useful in identifying a specific subpopulation of cells within a mixed colony. Accordingly, these molecules have been assigned a “cluster of differentiation” (CD) designation. T lymphocytes displaying the natural killer (NK) cell marker CD57 (also designated Leu7) on their cell surface are distinguishable from other T cell subsets by their granular lymphocyte morphology and their clonal expansion in patients with AIDS and in recipients of bone marrow transplantation. CD57+ cells have also been shown to localize to sites of certain tumors and large numbers of these cells are detected in the synovial fluid from patients suffering from rheumatoid arthritis.
Synonyms HNK-1, LEU7, NK-1, NK-Cell marker, NK1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.