COX17 Rabbit Polyclonal Antibody
Product Data | |
Application | IF, IHC, WB |
---|---|
Recommended Dilution | Western blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200. Immunofluorescence: 1/50-1/200. |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to the N-terminal of Human Cox-17. |
Specificity | This antibody detects endogenous levels of COX17 protein. (region surrounding Asn8) |
Buffer | PBS, pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% by SDS-PAGE) Preservative: 0.05% Sodium Azide |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography using epitope-specific immunogen |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | ~ 7 kDa |
Gene Name | COX17 cytochrome c oxidase copper chaperone |
Database Link | |
Background | Cytochrome c oxidase 17 (COX17) is a nuclear gene encoding an assembly protein necessary for proper COX apoenzyme-dependent mitochondrial respiration. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial genes that encode catalytic subunits and several nuclear genes that encode structural subunits. COX17 influences the recruitment of copper to the mitochondria for incorporation into the COX apoenzyme. |
Synonyms | COX-17 |
Reference Data | |
Protein Pathways | Metabolic pathways, Oxidative phosphorylation |
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