LMX1B Rabbit Polyclonal Antibody

CAT#: AP20515PU-N

LMX1B rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of LMX1B antibody (Cat.-No.: AP20515PU-N) in extracts from hela cells.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of LMX1B protein.
  (region surrounding Asp159)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 15 mM sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 42 kDa
• Gene Name: LIM homeobox transcription factor 1 beta
• Database Link:
  Entrez Gene 16917 MouseEntrez Gene 4010 Human
  UniProt ID O60663
• Background: The Lim class homeobox gene Lmx1b is required for the normal development of the dopaminergic system. Loss of dopaminergic neurons is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons play an important role in the control of multiple brain functions including voluntary movement alongside an array of behavioral processes such as mood, reward, addiction, and stress. Lmx1b is one of several transcription factors involved in the generation of dopaminergic neurons in the brain.
• Synonyms: LMX1B, LIM homeobox transcription factor 1-beta, LIM/homeobox protein LMX1B, LIM/homeobox protein 1.2, LMX-1.2

Reference Data

• Protein Families: Transcription Factors