KLF1 (+GKLF) Rabbit Polyclonal Antibody
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Specificity | This antibody detects endogenous levels of EKLF/GKLF protein. (region surrounding Trp318) |
| Buffer | Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | 1.0 mg/ml |
| Purification | Affinity chromatography (> 95% (by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 38 kDa |
| Gene Name | Kruppel-like factor 1 (erythroid) |
| Database Link | |
| Background | The Kruppel-type zinc finger transcription factors comprise a conserved family of DNA binding proteins that are important in developmental regulation. The Kruppel zinc finger transcription factor was initially identified in Drosophila as a segmentation gene. Kruppel-like factors that have been characterized in mammals include EKLF, LKLF and GKLF (6-8). EKLF is expressed principally in erythroid tissues, and LKLF expression is limited to the lung. GKLF is found predominantly in gut and has been shown to be expressed during growth arrest. |
| Synonyms | KLF1, EKLF, Krueppel-like factor 1, Erythroid transcription factor, KLF-1 |
| Reference Data | |
| Protein Families | Transcription Factors |
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