FLCN Rabbit Polyclonal Antibody
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/100 - 1/500. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide selected from the Center region of human FLCN |
| Specificity | This antibody reacts to FLCN. |
| Buffer | PBS with 0.09% (W/V) sodium azide State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Affinity chromatography on Protein A |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | folliculin |
| Database Link | |
| Background | FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). FLCN may be a tumor suppressor. May be involved in colorectal tumorigenesis. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. |
| Synonyms | FLCN, BHD |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Renal cell carcinoma |
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