CACNA2D1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP17917PU-N

CACNA2D1 (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of CACNA2D1 Antibody (N-term) in mouse brain tissue lysates (35ug/lane). CACNA2D1 (arrow) was detected using the purified Pab.

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  CACNA2D1 Antibody (N-term) Flow Cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Flow Cytometry: /10-1/50.
  Western blotting: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human CACNA2D1
• Specificity: This antibody CACNA2D1 (N-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: calcium voltage-gated channel auxiliary subunit alpha2delta 1
• Database Link:
  Entrez Gene 781 Human
  UniProt ID P54289
• Background: CACNA2D1 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.
• Synonyms: CACNL2A, CCHL2A, MHS3
• Note: Calculated Molecular Weight: 123183 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway