NDUFS4 (C-term) Rabbit Polyclonal Antibody

SKU AP17586PU-N

NDUFS4 (C-term) rabbit polyclonal antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.; Western blotting: 1/100 - 1/500.; Immunohistochemistry on paraffin sections: 1/50 - 1/100.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human NDUFS4
• Specificity: This antibody reacts to NDUFS4.
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: NADH:ubiquinone oxidoreductase subunit S4
• Database Link:
  O43181
• Background: NDUFS4 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase(Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane.
• Synonyms: Complex I-18 kDa, CI-18 kDa, Complex I-AQDQ, CI-AQDQ

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease