HLA class II DR beta 1 / HLA-DRB1 (N-term) Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | Western blot: 1:100 - 1:500. ELISA: 1:1,000. |
Reactivity | Human |
Antibody Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide selected from the N-terminal region of human HLA-DRB1 |
Specificity | This antibody detects HLA-DRB1 at N-term. |
Buffer | PBS with 0.09% (W/V) sodium azide State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Purified through a protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Database Link | |
Background | HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. |
Synonyms | MHC class II antigen DRB1, DR1, DR-1 |
Note | Molecular weight: 29914 Da |
Reference Data |
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