HLA class II DR beta 1 / HLA-DRB1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP17469PU-N

HLA class II DR beta 1 / HLA-DRB1 (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of HLA-DRB1 Antibody (N-term) (AP17469PU-N) in WiDr cell line lysates (35 g/lane). HLA-DRB1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:100 - 1:500.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human HLA-DRB1
• Specificity: This antibody detects HLA-DRB1 at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID P04229
• Background: HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons.
• Synonyms: MHC class II antigen DRB1, DR1, DR-1
• Note: Molecular weight: 29914 Da