FKBP1B (N-term) Rabbit Polyclonal Antibody

CAT#: AP17382PU-N

FKBP1B (N-term) rabbit polyclonal antibody

Product Images

(LEFT) Western blot analysis of FKBP1B antibody (N-term) in 293 cell line lysates (35 ug/lane). FKBP1B (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of FKBP1B antibody (N-term) in mouse cerebellum tissue lysates (35 ug/lane). FKBP1B (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:50 - 1:100.
  ELISA: 1:1,000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human FKBP1B
• Specificity: This antibody detects FKBP1B at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: FK506 binding protein 1B
• Database Link:
  Entrez Gene 2281 Human
  UniProt ID P68106
• Background: FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.
• Synonyms: FKBP12.6, FKBP1L, OTK4, PPIase FKBP1B, FK506-binding protein 1B, Rotamase, Immunophilin FKBP12.6, h-FKBP-12
• Note: Molecular weight: 11783 Da

Reference Data

• Protein Families: Druggable Genome