Biglycan (BGN) (Center) Rabbit Polyclonal Antibody
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | Western blot: 1/50 - 1/100. ELISA: 1/1,000. Immunohistochemistry on paraffin sections: 1/50 - 1/100. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 155~184 amino acids selected from the Center region of human BGN |
| Specificity | This antibody detects Biglycan at Center. |
| Buffer | PBS containing 0.09% (W/V) sodium azide as preservative State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
| Conjugation | Unconjugated |
| Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | biglycan |
| Database Link | |
| Background | BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival. |
| Synonyms | Bone/cartilage proteoglycan I, PG-S1, PGS1, BGN, SLRR1A |
| Note | Molecular weight: 41654 Da |
| Reference Data | |
| Protein Families | Secreted Protein |
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