PAK5 Rabbit Polyclonal Antibody

SKU AP14809PU-N

PAK5 rabbit polyclonal antibody, Purified

Product Data

• Application: IHC, IP, WB
• Recommended Dilution: ELISA: 1/1,000.; Western blotting: 1/100 - 1/500.; Immunoprecipitation: 1/100.; Immunohistochemistry: 1/10 - 1/50.; Flow cytometry.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 183~198 of human PAK5.
• Specificity: This antibody reacts to PAK5.
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Purified; State: Liquid purified Ig
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: p21 (RAC1) activated kinase 7
• Database Link:
  Q9P286
• Background: PAK5 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression.
• Synonyms: p21-activated kinase 7, PAK-7, p21-activated kinase 5, PAK-5, KIAA1264

Reference Data