FKBP1B (N-term) Rabbit Polyclonal Antibody

CAT#: AP14715PU-N

FKBP1B (N-term) rabbit polyclonal antibody, Purified

Product Images

LEFT: Western blot analysis of anti-FKBP1B Antibody (N-term) in CEM cell line lysates (35 ug/lane). FKBP1B (arrow) was detected using the purified Pab. RIGHT: Western blot analysis of anti-FKBP1B Antibody (N-term) in Mouse cerebellum tissue lysates (35 ug/lane). FKBP1B (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50-1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Human FKBP1B.
• Specificity: This antibody recognizes FKBP1B.
• Formulation: PBS with 0.09% (W/V) Sodium Azide
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: FK506 binding protein 1B
• Database Link:
  Entrez Gene 2281 Human
  UniProt ID P68106
• Background: FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.
• Synonyms: FKBP12.6, FKBP1L, OTK4, PPIase FKBP1B, FK506-binding protein 1B, Rotamase, Immunophilin FKBP12.6, h-FKBP-12
• Note: Calculated Molecular Weight: 11783 Da