RASGRF1 Rabbit Polyclonal Antibody

SKU AP14236PU-N

RASGRF1 rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC
• Recommended Dilution: ELISA: 1/1,000.; Immunohistochemistry: 1/10 - 1/50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S929 of human RASGRF1.
• Specificity: This antibody reacts to RASGRF1.
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Aff - Purified; State: Liquid purified Ig
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: Ras protein specific guanine nucleotide releasing factor 1
• Database Link:
  Q13972
• Background: RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
• Synonyms: Ras-GRF1, GRF1, GNRP, CDC25

Reference Data