MMP25 (C-term) Rabbit Polyclonal Antibody

SKU AP13179PU-N

MMP25 (C-term) rabbit polyclonal antibody, Purified

Product Data

• Application: WB
• Recommended Dilution: Peptide ELISA: 1/1,000.; Western blotting: 1/1,000.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP25.
• Specificity: This antibody reacts to MMP25.
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Purified; State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: matrix metallopeptidase 25
• Database Link:
  Q9NPA2
• Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP25 is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. In addition, it is thought that this protein is activated intracellularly by furin-like enzymes. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP20 but has been renamed matrix metalloproteinase 25 (MMP25).
• Synonyms: Matrix metalloproteinase-25, MMP25, MMP20, MMPL1, MT6MMP, Leukolysin, MT6-MMP, MT-MMP 6

Reference Data