LEO1 pSer10 Rabbit Polyclonal Antibody
| Product Data | |
| Recommended Dilution | ELISA: 1/1,000. Dot Blot: 1/500. |
|---|---|
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | Ig |
| Clonality | Polyclonal |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human LEO1. |
| Specificity | This antibody detects LEO1 pSer10. |
| Buffer | PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction. |
| Concentration | lot specific |
| Purification | Protein A Chromatography followed by two-step phosphospecific peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | LEO1 homolog, Paf1/RNA polymerase II complex component |
| Database Link | |
| Background | The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. May be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts. |
| Synonyms | LEO-1, RDL |
| Note | Molecular weight: 75273 Da |
| Reference Data | |
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