LEO1 pSer10 Rabbit Polyclonal Antibody

CAT#: AP12991PU-N

LEO1 pSer10 rabbit polyclonal antibody, Aff - Purified

Product Images

Dot blot analysis of anti-Phospho-LEO1 pSer10 Antibody (Cat.#AP12991PU-N) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Specifications

Product Data

• Recommended Dilution: ELISA: 1/1,000.
  Dot Blot: 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human LEO1.
• Specificity: This antibody detects LEO1 pSer10.
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: LEO1 homolog, Paf1/RNA polymerase II complex component
• Database Link:
  Entrez Gene 123169 Human
  UniProt ID Q8WVC0
• Background: The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. May be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.
• Synonyms: LEO-1, RDL
• Note: Molecular weight: 75273 Da