ACOX1 (N-term) Rabbit Polyclonal Antibody
ACOX1 (N-term) rabbit polyclonal antibody, Purified
|Recommended Dilution||ELISA: 1/1,000.
Western Blot: 1/1,000.
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ACOX1.|
|Specificity||This antibody is specific to ACOX1 (N-term).|
|Formulation||PBS with 0.09% (W/V) Sodium Azide as preservative.
State: Liquid purified Ig fraction.
|Purification||Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Gene Name||acyl-CoA oxidase 1, palmitoyl|
|Background||ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.|
|Synonyms||AOX, Palmitoyl-CoA oxidase, Straight-chain acyl-CoA oxidase|
|Note||Calculated Molecular weight: 74442 Da|