NMD3 (C-term) Rabbit Polyclonal Antibody

SKU AP11767PU-N

NMD3 (C-term) rabbit polyclonal antibody, Purified

Product Data

• Application: WB
• Recommended Dilution: ELISA 1:1,000.; Western blot 1:100 - 1:500.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NMD3.
• Specificity: This antibody detects NMD3 at C-term.
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Purified; State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: NMD3 ribosome export adaptor
• Database Link:
  Q96D46
• Background: It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.
• Synonyms: hNMD3,CGI-07
• Note: Molecular weight: 57603 Da

Reference Data