CSEN (KCNIP3) (N-term) Rabbit Polyclonal Antibody

SKU AP11608PU-N

CSEN (KCNIP3) (N-term) rabbit polyclonal antibody, Purified

Product Data

• Application: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA: 1/1,000.; Western blot: 1/1,000. ; Immunofluorescence: 1/10-1/50.; Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Human KChIP3.
• Specificity: This antibody detects KChIP3 at N-term.
• Buffer: PBS with 0.09% (W/V) Sodium Azide; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C fore month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: potassium voltage-gated channel interacting protein 3
• Database Link:
  Q9Y2W7
• Background: KChIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. Due to utilization of an alternate in-frame translation start codon, the gene for this protein encodes two isoforms with different sizes.
• Synonyms: KCNIP3, CSEN, DREAM, KCHIP3, DRE-antagonist modulator
• Note: Calculated Molecular weight: 29231 Da

Reference Data