KREMEN1 (N-term) Rabbit Polyclonal Antibody
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | ELISA 1:1,000. Western blot 1:100 - 1:500. Immunohistochemistry 1:50 - 1:100. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | Ig |
| Clonality | Polyclonal |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Kremen. |
| Specificity | This antibody detects Kremen at N-term. |
| Buffer | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS |
| Conjugation | Unconjugated |
| Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | kringle containing transmembrane protein 1 |
| Database Link | |
| Background | Kremen is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. |
| Synonyms | KREMEN1, KREMEN, KRM1, Dickkopf receptor |
| Note | Molecular weight: 63,201 Da (Isoform 3) |
| Reference Data | |
Write Your Own Review
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.