APOBEC1 (N-term) Rabbit Polyclonal Antibody

SKU AP11344PU-N

APOBEC1 (N-term) rabbit polyclonal antibody, Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA: > 1/1,000 (peptide only); Western blot: 1/1000; Immunohistochemistry: 1/50-1/100.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Apobec1.
• Specificity: This antibody is specific to APOBEC1 (N-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative.; State: Purified; State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: apolipoprotein B mRNA editing enzyme catalytic subunit 1
• Database Link:
  P41238
• Background: APOBEC1 is involved in the production of apolipoprotein B (apoB)-48 from apoB-100. The gene spans 18 kb and contains five exons, all of which are translated. Alternative splicing produces a variant transcript that lacks exon 2 and encodes a novel 36-amino acid peptide. The exon 2-skipped transcript accounts for approximately 50% of APOBEC1 mRNA in the adult small intestine and up to 90% of APOBEC1 mRNA in the developing gut. Exon 2-skipping may thus be a quantitatively important mechanism for regulating the expression of this gene in the gastrointestinal tract.
• Synonyms: HEPR, APOBEC-1
• Note: Calculated MW: 28173 Da

Reference Data