TRF41 (PAPD7) (447-462) Rabbit Polyclonal Antibody
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1 - 2 µg/ml. |
| Reactivity | Human, Monkey |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide containing amino acids 447-462 of human TRF4-1 |
| Specificity | This antibody recognizes Polymerase (DNA Directed) Sigma (POLS/TRF4-1) at aa 447-462. |
| Buffer | PBS containing 0.2% Gelatin as stabilizer and 0.05% Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Protein G Chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | PAP associated domain containing 7 |
| Database Link | |
| Background | Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation. |
| Synonyms | DNA polymerase sigma, DNA polymerase kappa, TRF-4, LAK-1, TUTase5 |
| Reference Data | |
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