NALP1 (NLRP1) Rabbit Polyclonal Antibody

CAT#: AP07775PU-N

NALP1 (NLRP1) rabbit polyclonal antibody, Purified

Product Images

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Brain, Cortex.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunocytochemistry.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot: 1 - 2 µg/ml.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic Peptide corresponding to 13 amino acids near the carboxy-terminus of human NALP1
• Specificity: This antibody detects NALP1 (CARD7).
• Formulation: Phosphate Buffered Saline PBS containing 0.02% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: IgG Fractionation.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or
  (in aliquots) at -20°C for longer.
  Dilute only prior to immediate use.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: NLR family, pyrin domain containing 1
• Database Link:
  Entrez Gene 22861 Human
  UniProt ID Q9C000
• Background: Death Effector Filament-forming Ced 4 like Apoptosis Protein (DEFCAP) is a novel apoptotic protein of the mammalian Ced 4 family. It has two isoforms: DEFCAP-Land DEFCAP-S. The deduced amino acid sequences of these two alternately spliced isoforms only differ by 44amino acids at the C-terminus. DEFCAP contains a caspase recruitment domain (CARD), a domain that with the proper stimulation can recruit caspases to form cytoplasmic structures called death effector filaments, which in turn initiate the apoptotic signaling pathway.
• Synonyms: DEFCAP, KIAA0926, NAC, NALP1