BACH1 (Isoform 1) (92-104) Rabbit Polyclonal Antibody
Product Data | |
Application | ELISA, IF, IHC, WB |
---|---|
Recommended Dilution | ELISA: 1/10000 - 1/44000. Immunofluorescence. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1/500 - 1/2000. |
Reactivity | Human, Monkey, Mouse, Rat |
Antibody Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant human BACH1 , aa 92-104 |
Specificity | This antibody reacts to the amino acids 92-104 of isoform 1 of BACH1 protein. |
Buffer | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01% (w/v) Sodium Azide State: Aff - Purified State: Liquid purified Ig |
Concentration | lot specific |
Purification | Immunoaffinity Chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | BTB domain and CNC homolog 1 |
Database Link | |
Background | BACH1 (also known as BRCA1 interacting protein C-terminal helicase 1, BRCA1-interacting protein 1 and BRCA1-associated C-terminal helicase 1) is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). The BACH1 gene may be a target of germline cancer-inducing mutations. BACH1 is localized within the nucleus and functions as a DNA-dependent ATPase and 5' to 3' DNA helicase. Two isoforms have been identified for this protein. |
Synonyms | HA2303 |
Reference Data |
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