alpha 2C Adrenergic Receptor (ADRA2C) Rabbit Polyclonal Antibody
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | Western blot: 1/500-1/1000. Immunohistochemistry on paraffin sections: 1/50-1/200. Immunofluorescence: 1/50-1/200. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide, corresponding to amino acids 340-390 of Human AR-α2C. |
| Specificity | This antibody detects endogenous levels of AR alpha2C protein. (region surrounding Arg369) |
| Buffer | Phosphate buffered saline (PBS), pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide |
| Concentration | 1.0 mg/ml |
| Purification | Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 70 kDa |
| Gene Name | adrenoceptor alpha 2C |
| Database Link | |
| Background | Alpha-2C adrenergic receptors (alpha2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. alpha2C-AR can influence Parkinson’s disease, panic disorders, and Huntington disease (HD) progression. alpha2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney. |
| Synonyms | ADRA2L2, ADRA2RL2, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor |
| Reference Data | |
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