Steroidogenic Factor 1 (NR5A1) Rabbit Polyclonal Antibody

CAT#: AP06579PU-N

Steroidogenic Factor 1 (NR5A1) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of SF1 antibody in extracts from HeLa cells treated with TNF-a 20ng/ml 2'.

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  Immunohistochemistry (IHC) analyzes of SF1 antibody in paraffin-embedded human braintissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 45-98 of Human SF1.
• Specificity: This antibody detects endogenous levels of SF1 protein.
  (region surrounding Pro76)
• Formulation: Phosphate Buffered Saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Predicted Protein Size: ~68 kDa
• Gene Name: nuclear receptor subfamily 5 group A member 1
• Database Link:
  Entrez Gene 2516 Human
  UniProt ID Q13285
• Background: Steroidogenic factor-1 (SF-1) regulates multiple genes involved in the adrenal and gonadal development and in the biosynthesis of a variety of hormones, including adrenal and gonadal steroids, anti-Mullerian hormone (AMH), and gonadotropins. SF-1 belongs to the fushi tarazu factor-1 (FTZ-F1) subfamily of orphan nuclear receptors. In the adult ovary, SF-1 localizes to theca/interstitial cells.
• Synonyms: STF-1, SF-1,NR5A1, AD4BP, FTZF1, SF1