GABA B Receptor 1 (GABBR1) Rabbit Polyclonal Antibody

SKU AP06128PU-N

GABA B Receptor 1 (GABBR1) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.; Immunohistochemistry: 1/50-1/200.
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 870-913 of Human GABAB R1.
• Specificity: This antibody detects endogenous levels of GABA-B Receptor protein.; (region surrounding Ile902)
• Buffer: Phosphate buffered saline (PBS), pH 7.2.; State: Aff - Purified; State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).; Preservative: 0.05% Sodium azide
• Concentration: <span>1.0 mg/ml</span>
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: ~ 110 kDa
• Gene Name: gamma-aminobutyric acid type B receptor subunit 1
• Database Link:
  Q9UBS5
• Background: GAD-65 and GAD-67, glutamate decarboxylases of 65 kDa and 67 kD,arespectively, function to catalyze the production of GABA (gamma-aminobutyricacid). In the central nervous system GABA (gamma-aminobutyric acid)functions as the main inhibitory transmitter by increasing a Cl-conductancethat inhibits neuronal firing. GABA has been shown to activate bothionotropic (GABAA) and metabotropic (GABAB) receptors as well as a thirdclass of receptors called GABAC.; The inhibitory neurotransmitter, GABA, acts through two ligand gated channels, GABAa and GABAc receptors and GABAb, the latter of which acts through a G protein mechanism. GABAbR1 is one of two G protein coupled receptors for GABAb that acts as a heteromeric assembly with GABAbR2.
• Synonyms: GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, GPRC3A

Reference Data