AP2 alpha (TFAP2A) Rabbit Polyclonal Antibody

SKU AP06013PU-N

AP2 alpha (TFAP2A) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.; Immunohistochemistry on Paraffin sections: 1/50-1/200.
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 401-450 of Human TFAP2A.
• Specificity: This antibody detects endogenous levels of TFAP2A / AP-2 alpha protein (region surrounding Lys431).
• Buffer: Phosphate buffered saline (PBS), pH 7.2; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.05% Sodium azide
• Concentration: 1.0 mg/ml
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen (> 95%pure by SDS-PAGE).
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: ~50 kDa
• Gene Name: transcription factor AP-2 alpha
• Database Link:
  P05549
• Background: The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer.AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
• Synonyms: AP2TF, TFAP2, AP-2 transcription factor, Activator protein 2, AP2

Reference Data