EDA2R Rabbit Polyclonal Antibody

SKU AP05597PU-N

EDA2R rabbit polyclonal antibody, Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: Western blot: 0.5 - 2.0 µg/ml; detects a band of approximately 33kDa in 293 cell lysates.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant human XEDAR.
• Specificity: This antibody detects human X-linked ectodermal dysplasia receptor (XEDAR).
• Buffer: Phosphate buffered saline containing 0.02% Sodium Azide; State: Purified; State: Liquid purified IgG
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for up to one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: ectodysplasin A2 receptor
• Database Link:
  Q9HAV5
• Background: XEDAR is a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist; XEDAR-s and XEDAR-L, produced by alternative splicing.
• Synonyms: XEDAR, EDA-A2 receptor, UNQ2448/PRO5727/PRO34080

Reference Data