GLI1 Rabbit Polyclonal Antibody

CAT#: AP05303PU-N

GLI1 rabbit polyclonal antibody, Aff - Purified


USD 514.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications WB
Recommended Dilution Western blot (1:400 starting dilution).
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide derived from human zinc finger protein GLI1
Specificity This antibody detects Zinc Finger Protein GLI1, found in testis, myometrium and fallopian tube.
Formulation Phosphate buffered saline with 0.08% sodium azide
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography
Conjugation Unconjugated
Storage Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
Avoid repeated freezing and thawing.
Stability Shelf life: One year from despatch.
Background Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes during normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer.
Synonyms GLI-1, GLI
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.