ROBO1 Rabbit Polyclonal Antibody

CAT#: AP05287PU-N

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Rabbit Polyclonal Anti-ROBO1 Antibody, Aff - Purified

 Product Datasheet for 'AP05287PU-N'

USD 400.00

2 Weeks

    • 100 ug

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Product Data
Applications WB
Recommend Dilution WB
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide derived from human ROBO1 protein
Formulation Phosphate buffered saline with 0.08% sodium azide
Concentration Lot specific
Purification Affinity chromatography
Predicted Protein Size 175.7 kDa
Gene Name roundabout guidance receptor 1
Background Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line.
Synonyms DUTT1; SAX3
Reference Data
Protein Families Druggable Genome
Protein Pathways Axon guidance
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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BOGO Free lysates
68 Mouse Clones