ROBO1 Rabbit Polyclonal Antibody

CAT#: AP05287PU-N

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ROBO1 rabbit polyclonal antibody, Aff - Purified


Product Datasheet for 'AP05287PU-N'


USD 360.00


Availability*
5 Days

Size
    • 100 ug


Product images

Specifications

Product Data
Applications WB
Recommended Dilution Western blot (1:400 starting dilution).
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide derived from human ROBO1 protein
Specificity This antibody detects Roundabout homolog 1 / ROBO1, widely expressed, with exception of kidney.
Formulation Phosphate buffered saline with 0.08% sodium azide
State: Aff - Purified
State: Liquid Ig fraction
Concentration Lot specific
Purification Affinity chromatography
Background Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line.
Synonyms ROBO-1, Roundabout homolog 1, DUTT1
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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