UGT8 Rabbit Polyclonal Antibody
| Product Data | |
| Application | ELISA, WB |
|---|---|
| Recommended Dilution | ELISA. Western Blot: 5-10 µg/ml. Positive Control: Found in all tissues examined. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide derived from Human Ceramide Glycosyltransferase Protein |
| Specificity | This antibody recognizes Human Ceramide Glycosyltransferase. Other species not tested. |
| Buffer | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.08% Sodium Azide |
| Concentration | lot specific |
| Purification | Ammonium Sulfate Precipitation |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | UDP glycosyltransferase 8 |
| Database Link | |
| Background | May serve as a flippase as well as a glucosyltransferase that transfers glucose to ceramide. It Catalzes; UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates. |
| Synonyms | UDP-galactose-ceramide galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, CGT |
| Reference Data | |
| Protein Families | Transmembrane |
| Protein Pathways | Metabolic pathways, Sphingolipid metabolism |
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