Sphingosine 1 phosphate phosphatase 2 (SGPP2) Rabbit Polyclonal Antibody

SKU AP05170PU-N

Sphingosine 1 phosphate phosphatase 2 (SGPP2) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution: Western Blot: 1:400; Tissue lysate should be used at 10 - 50 µg/lane.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from the sphingosine 1-phosphate phosphatase 2 protein.
• Specificity: This antibody reacts to Sphingosine 1-Phosphate Phosphatase 2.
• Buffer: Phosphate buffered saline with 0.08% sodium azide; State: Aff - Purified; State: Liquid purified
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Ship on dry ice. Store (in aliquots) at -20°C only.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: sphingosine-1-phosphate phosphatase 2
• Database Link:
  Q8IWX5
• Background: Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1 - 5)/Gprotein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. SPPase2 is localized to the endoplasmic reticulum. The enzymatic activity and localization of SPPase2 are similar to SPPase1. The tissue expression of SPPase2 was different from that of SPPase1. SPPase2 is an important member of the SPPase family which play a role in attenuating intracellular S1P signaling.
• Synonyms: Sphingosine-1-phosphatase 2, SPPase2

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Sphingolipid metabolism