sphingosine 1 phosphate phosphatase 1 (SGPP1) Rabbit Polyclonal Antibody

SKU AP05169PU-N

sphingosine 1 phosphate phosphatase 1 (SGPP1) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution: Western Blot: 1:200; Tissue lysate should be used at 10-50 µg/lane.; Positive Control: Human brain lysate.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from the sphingosine 1-phosphate phosphatase 1 protein.
• Specificity: This antibody reacts to Sphingosine 1-Phosphate Phosphatase 1.
• Buffer: Phosphate buffered saline with 0.08% sodium azide; State: Aff - Purified; State: Liquid purified Ig
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: The antibody can be shipped on dry ice. Store (in aliquots) at -20°C only.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: sphingosine-1-phosphate phosphatase 1
• Database Link:
  Q9BX95
• Background: Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. Regulation of hS1Pase1 with the resultant changes in cellular and secreted S1P has important implications in cell proliferation, angiogenesis and apoptosis.
• Synonyms: Sphingosine-1-phosphatase 1, SPPase1

Reference Data

• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Protein Pathways: Sphingolipid metabolism