Arhgef2 Sheep Polyclonal Antibody

SKU AP05081PU-N

Arhgef2 sheep polyclonal antibody, Purified

Product Data

• Application: IF, IP, WB
• Recommended Dilution: Western Blot: 4 µg/ml. Detects a 118 kDa band in Mouse tissue extracts corresponding to wild-type LFC.; Immunoprecipitation: 4 µg/ml.; Immunofluorescence.
• Reactivity: Mouse
• Antibody Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Antibody developed using protein corresponding to amino acids 2 to 447 of the Lfc protein fused to GST.
• Specificity: This antibody recognizes LCF.
• Buffer: Phosphate Buffered Saline and 0.08% Sodium Azide; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: The antibody can be shipped at ambient temperature.; Store (in aliquots) at -20°C only.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: rho/rac guanine nucleotide exchange factor (GEF) 2
• Database Link:
  Q60875
• Background: Lfc is a 118 kDa protein discovered in a screen for oncogenes in NIH 3T3 cells. Lfc is a signaling protein related to Lbc and is part of the Dbl family of proteins. Lfc is a guanine-nucleotide exchange factor (GEF) for the Rho family of small GTPases. Lfc has also been shown to be upstream of the serine-threonine kinase JNK. Lfc has also been shown to mediate the activation of the Rac signaling pathway.
• Synonyms: KIAA0651, LFP40, GEF-H1

Reference Data