PKC delta (PRKCD) Rabbit Polyclonal Antibody

CAT#: AP02781PU-S

PKC delta (PRKCD) rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul


USD 312.00

2 Weeks*

Size
    • 50 ul

Product Images

Other products for "PRKCD"

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution Western blot: 1/500~1/1000.
Immunofluorescence: 1/100~1/200.
Immunohistochemistry on Paraffin-Embedded Sections: 1/50~1/100.
Reactivities Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around amino acids 643~647 (R-L-Sp-Y-S) derived from Human PKC-delta
Specificity This antibody detects endogenous levels of total PKC-delta protein.
Formulation PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Immunoaffinity Chromatography using epitope-specific immunogen.
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background Protein Kinase C delta (PKC delta) is a 78 kDa member of the novel group (nPKCs: sensitive to diacylglycerol, phosphatidylserine, and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC delta is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of multiple cellular processes including cell cycle progression and apoptosis. Autophosphorylation of serine 664 (serine 662 in mouse and rat) contributes to PKC delta activity. Serum dependent phosphorylation of serine 664 is mediated by mTOR pathway, is protected from dephosphorylation by phosphorylated threonine 505 in the activation loop, and is implicated in prolactin signaling.
Synonyms PKC-delta, PKC delta, PKCD, Protein kinase C delta type
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.