5HT5A receptor (HTR5A) Rabbit Polyclonal Antibody

CAT#: AP01292PU-N

Rabbit Polyclonal Anti-HTR5A Antibody, Aff - Purified

 Product Datasheet for 'AP01292PU-N'

USD 370.00

2 Weeks

    • 0.1 mg

Product images


Product Data
Applications WB
Recommend Dilution ELISA, ICC/IF, WB
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids N-terminus of Human SR-5A.
Isotype IgG
Formulation Phosphate buffered saline (PBS), pH 7.2
Concentration 1 mg/ml
Purification Affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Predicted Protein Size 40.1 kDa
Gene Name 5-hydroxytryptamine receptor 5A
Background SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134) is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus. Serotonin receptors include SR-1¨C7 (5HT1¨C7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B. SR receptors can couple to G proteins that act on either adenylate cyclase or phospholipase C (PLC). The SR-3 class of receptors are ion channels.
Synonyms 5-HT5A
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction
Other products for "HTR5A"
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Antibody Performance Guarantee banner
40% off proteins and antibodies
68 Mouse Clones