MC1 Receptor (MC1R) Rabbit Polyclonal Antibody

SKU AP01272PU-N

MC1 Receptor (MC1R) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IF, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.; Immunofluorescence: 1/50-1/200.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 300-350 of Human MC1-R.
• Specificity: This antibody detects endogenous levels of MC1-R protein (region surrounding Val312).
• Buffer: PBS, pH~7.2 with 50% Glycerol; State: Aff - Purified; State: Liquid purified Ig fraction (>95% pure by SDS-PAGE); Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: ~35 kDa
• Gene Name: melanocortin 1 receptor
• Database Link:
  Q01726
• Background: The melanocortin family comprises the alpha-, beta- and gamma-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.
• Synonyms: Melanotropin receptor, Melanocortin receptor 1, MC1R, MSHR, MSH-R

Reference Data