HRH1 Rabbit Polyclonal Antibody

SKU AP01271PU-N

HRH1 rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IF, WB
• Recommended Dilution: Western blot: 1/500-1/1000.; Immunofluorescence: 1/50-1/200.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human Histamine H1 Receptor.
• Specificity: This antibody detects endogenous levels of Histamine H1 Receptor protein. (region surrounding Lys179)
• Buffer: Phosphate buffered saline (PBS), pH~7.2; State: Aff - Purified; State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).; Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: ~60 kDa
• Gene Name: histamine receptor H1
• Database Link:
  P35367
• Background: Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors, the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H1 Receptor maps to chromosome 3p25 and is expressed in highest abundance in placenta, with lower levels in lung, skeletal muscle, kidney and brain. The murine Histamine H2 Receptor gene maps to chromosome 13 and is highly expressed in stomach with moderate expression in brain and heart. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus. The human Histamine H4 Receptor gene maps to chromosome 18q11 and is expressed most abundantly in bone marrow and spleen in addition to peripheral blood leukocytes, thymus, small intestine and colon.
• Synonyms: HRH1, HR-H1, Histamine H1 receptor

Reference Data