PDE1A Rabbit Polyclonal Antibody

SKU AP00651SU-N

PDE1A rabbit polyclonal antibody, Serum

Product Data

• Application: IHC, IP, WB
• Recommended Dilution: Western blot (1/2000 as a guideline).; Immunoprecipitation.; Immunohistochemistry.
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Designed from the C-terminal region common to all known 1A isoforms.
• Specificity: The antibody selectively detects proteins corresponding to the PDE1A sub-family (See Figure 1).
• Buffer: PBS containing 0.05% Sodium Azide as preservative; State: Serum; State: Liquid Diluted Serum
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20 to -80°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 61 kDa (Predicted)
• Gene Name: phosphodiesterase 1A
• Database Link:
  P54750
• Background: Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3',5'-monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling.; PDE1 has three subtypes, PDE1A, PDE1B and PDE1C. PDE1A and PDE1B have higher affinity for cGMP than for cAMP, whereas PDE1C has high affinity for both cAMP and cGMP.
• Synonyms: Phosphodiesterase 1A, Phosphodiesterase-1A calmodulin-dependent, Cam-PDE 1A, HSPDE1A, HCAM1, hCam-1

Reference Data