PMVK Mouse Monoclonal Antibody [Clone ID: AT21C10]

SKU AM50615PU-N

PMVK mouse monoclonal antibody, clone AT21C10, Purified

Product Data

• Clone Name: AT21C10
• Application: ELISA, FC, IF, WB
• Recommended Dilution: The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
• Reactivity: Human
• Antibody Host: Mouse
• Clonality: Monoclonal
• Immunogen: Recombinant human PMVK (1-192aa) purified from E. coli.
• Buffer: Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: phosphomevalonate kinase
• Database Link:
  Q15126
• Background: Phosphomevalote kise, also known as PMVK, is a cytosolic enzyme. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalote pathway. PMVK catalyzes the conversion of mevalote 5-phosphate into mevalote 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.
• Synonyms: Phosphomevalonate kinase, PMKase, PMKI, HUMPMKI

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Terpenoid backbone biosynthesis