ABCC12 Rat Monoclonal Antibody [Clone ID: M9II-3]

CAT#: AM31989SU-N

ABCC12 rat monoclonal antibody, clone M9II-3, Supernatant

Specifications

Product Data

• Clone Name: M9II-3
• Applications: IF, IHC, WB
• Recommended Dilution: Western blotting: Use at 1/20-1/50 and anti-Rat-HRP.
  Immunocytochemistry: Use at 1/20-1/50 on Acetone Fixed Cytospin preparations.
  Immunohistochemisty on Frozen Sections: 1/20 on Acetone Fixed Frozen sections can be followed by incubation with Rabbit anti-Rat Ig (1/25) and a monoclonal Rat APAAP complex (1/50). Alternatively, after incubation with M9II-3 (use 1/20) and washing, slides can be incubated with biotinylated Rabbit anti-Rat Ig (1/100) and streptavidin conjugated to Horseradish Peroxidase (1/500).
• Reactivities: Human
• Host: Rat
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A bacterial fusion protein of Human MRP9, containing amino acids 690-734 of the protein.
• Specificity: This Monoclonal antibody M9II-3 reacts with an internal epitope of MRP9 (ABCC12), an approximately 150 kD transmembrane protein that is related to the multidrug resistance protein MRP1.
• Formulation: State: Supernatant
  State: Serum Free Culture Supernatant
  Stabilizer: 0.7% BSA
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store antibody undiluted at 2-8°C.
  
• Stability: Shelf life: one year from despatch.
• Gene Name: ATP binding cassette subfamily C member 12
• Database Link:
  Entrez Gene 94160 Human
  UniProt ID Q96J65
• Background: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
• Synonyms: Multidrug resistance-associated protein 9