EMILIN2 Rat Monoclonal Antibody [Clone ID: 828B3B3]
Specifications
| Product Data | |
| Clone Name | 828B3B3 |
|---|---|
| Application | FC, IP, WB |
| Recommended Dilution | Western Blot: Use at 1-5 µg/ml. IF/Immunohistochemistry on Frozen Sections. Immunoprecipitation. FACS Analysis. |
| Reactivity | Human |
| Antibody Host | Rat |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Recombinant protein gC1q domain of EMILIN-2. |
| Specificity | This antibody was selected for its ability to detect Human Emilin-2. |
| Buffer | PBS State: Purified State: Lyophilized (0.2 μm filtered) purified IgG fraction |
| Reconstitution Method | Centrifuge vial prior to opening. Restore in sterile water to the final concentration of 0.1-1.0 mg/ml. |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | elastin microfibril interfacer 2 |
| Database Link | |
| Background | Emilins (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine-rich EMI domain and a conserved C-terminal gC1q-like domain. Emilin-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as Emilin-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as Emilin-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. Emilin-5 is encoded by the Emilin-3 gene and is sometimes referred to as Emilin-3. It contains the N-terminal cysteine-rich EMI domain but lacks the C-terminal gC1q-like domain. Emilin-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development. |
| Synonyms | EMILIN-2, Protein FOAP-10 |
| Reference Data | |
| Protein Categories | Secreated Proteins |
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