EMILIN2 Rat Monoclonal Antibody [Clone ID: 828B3B3]

SKU AM31890PU-N

EMILIN2 rat monoclonal antibody, clone 828B3B3, Purified

Product Data

• Clone Name: 828B3B3
• Application: FC, IP, WB
• Recommended Dilution: Western Blot: Use at 1-5 µg/ml.; IF/Immunohistochemistry on Frozen Sections.; Immunoprecipitation.; FACS Analysis.
• Reactivity: Human
• Antibody Host: Rat
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant protein gC1q domain of EMILIN-2.
• Specificity: This antibody was selected for its ability to detect Human Emilin-2.
• Buffer: PBS; State: Purified; State: Lyophilized (0.2 μm filtered) purified IgG fraction
• Reconstitution Method: Centrifuge vial prior to opening.; Restore in sterile water to the final concentration of 0.1-1.0 mg/ml.
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at 2-8°C.; Following reconstitution store undiluted at 2-8°C for one month ; or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Ambient
• Gene Name: elastin microfibril interfacer 2
• Database Link:
  Q9BXX0
• Background: Emilins (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine-rich EMI domain and a conserved C-terminal gC1q-like domain. Emilin-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as Emilin-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as Emilin-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. Emilin-5 is encoded by the Emilin-3 gene and is sometimes referred to as Emilin-3. It contains the N-terminal cysteine-rich EMI domain but lacks the C-terminal gC1q-like domain. Emilin-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development.
• Synonyms: EMILIN-2, Protein FOAP-10

Reference Data