Thrombomodulin (THBD) Mouse Monoclonal Antibody [Clone ID: B-S24]

CAT#: AM31361AF-N

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Thrombomodulin (THBD) mouse monoclonal antibody, clone B-S24, Azide Free



USD 314.00


Availability*
2 Weeks

Size
    • 200 ug


Product images

Specifications

Product Data
Clone Name B-S24
Applications ELISA
Recommended Dilution ELISA.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Eahy 926 cell lines.
Specificity Recognises Thrombomodulin (TM), a 105 kDa protein.
Formulation 0.22 µm Sterile-filtered PBS. 
 Carrier and preservative free.
State: Azide Free
State: Liquid purified IgG fraction
Concentration lot specific
Purification Ion Exchange Chromatography
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for up to 12 months.
For longer storage freeze aliquots.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens thrombomodulin (THBD)
Background CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.
Synonyms Thrombomodulin, THRM, Fetomodulin
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Complement and coagulation cascades
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.