NCR1 Mouse Monoclonal Antibody [Clone ID: B-L46]

CAT#: AM31284AF-N

NCR1 mouse monoclonal antibody, clone B-L46, Azide Free

Product Images

CD107a surface expression on activated NK cells: IL-2 activated NK are cultured 4 hours on coated anti-NKp46 monoclonal antibody (A) or on IgG2a isotypic control (B).

Specifications

Product Data

• Clone Name: B-L46
• Applications: FC, FN
• Recommended Dilution: Flow Cytometry.
  Functional Assay: The biological activity is measured by the ability of the coated antibody to induce degranulation of activated NK cells and to enhance IFN-g secretion by non-activated NK.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant human NKp46/Fc (CD335)
• Specificity: This antibody recognises natural and recombinant NKp46.
• Formulation: Phosphate-buffered saline.
  Sterile filtered through 0.22µm and treated to remove endotoxins.
  Carrier and preservative free.
  State: Azide Free
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Ion Exchange Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: natural cytotoxicity triggering receptor 1
• Database Link:
  Entrez Gene 9437 Human
  UniProt ID O76036
• Synonyms: NCR1, LY94, NKp46

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity