IL9R Mouse Monoclonal Antibody [Clone ID: AH9R7]
Product Data | |
Clone Name | AH9R7 |
---|---|
Application | ELISA, FC, FN |
Recommended Dilution | Flow cytometry: Use bright fluorochromes or signal multiplying detection. ELISA. Functional application: blocking. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Human CD129-transfected cell line |
Specificity | This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. |
Buffer | Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 μm filter sterilized State: Low Endotoxin State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein-A affinity chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | interleukin 9 receptor |
Database Link | |
Background | CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma. |
Synonyms | Interleukin-9 receptor, IL-9R, IL-9 receptor |
Reference Data |
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