CD300E Mouse Monoclonal Antibody [Clone ID: UP-H2]
Product Data | |
Clone Name | UP-H2 |
---|---|
Application | FC, FN, IP, WB |
Recommended Dilution | Flow cytometry. Immunoprecipitation. Western blot. Functional application: stimulation. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | CD300e-HA-transfected cells |
Specificity | This antibody recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells. |
Buffer | Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4 |
Concentration | lot specific |
Purification | Protein-A affinity chromatography (> 95% pure by SDS-PAGE) |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | CD300e molecule |
Database Link | |
Background | CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers. |
Synonyms | CLM-2, CD300LE, CLM2, IREM2, CMRF35-A5 |
Reference Data |
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