SLAMF1 Mouse Monoclonal Antibody [Clone ID: SLAM.4]

CAT#: AM26146AF-N

SLAMF1 mouse monoclonal antibody, clone SLAM.4, Azide Free

Specifications

Product Data

• Clone Name: SLAM.4
• Applications: FC, IF, IP
• Recommended Dilution: Flow cytometry: Recommended dilution: 1-5 μg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human CD150-transfected 300.19 cells.
• Specificity: This Monoclonal SLAM.4 antibody recognizes CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.
• Formulation: Azide free phosphate buffered saline (PBS), pH~7.4, 0.2 μm filter sterilized
  State: Azide Free
  State: Liquid purified IgG fraction (> 95% pure by SDS-PAGE)
• Concentration: lot specific
• Purification: Aaffinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: signaling lymphocytic activation molecule family member 1
• Database Link:
  Entrez Gene 6504 Human
  UniProt ID Q13291
• Background: CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.
• Synonyms: Slam, CDw150, Ipo-3

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane